Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM339995'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM339995 (5-[(2-Aminoethyl)amino]-3-(5-fluoro-1H-indol-2-yl)...) Show SMILES NCCNc1cnc(C(N)=O)c(n1)-c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C15H15FN6O/c16-9-1-2-10-8(5-9)6-11(21-10)13-14(15(18)23)20-7-12(22-13)19-4-3-17/h1-2,5-7,21H,3-4,17H2,(H2,18,23)(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...				US Patent US9775839 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RN9
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