Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM340007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM340007 ((2-(6-(((3S,4S)-4-amino-1,1-dioxidotetrahydro-2H-t...) Show SMILES C[S+](C)c1c([nH]c2ccccc12)-c1nc(N[C@@H]2CS(=O)(=O)CC[C@@H]2N)cnc1C(N)=O Show InChI InChI=1S/C20H24N6O3S2/c1-30(2)19-11-5-3-4-6-13(11)25-17(19)16-18(20(22)27)23-9-15(26-16)24-14-10-31(28,29)8-7-12(14)21/h3-6,9,12,14H,7-8,10,21H2,1-2H3,(H3-,22,24,25,26,27)/p+1/t12-,14+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...				US Patent US9775839 (2017) BindingDB Entry DOI: 10.7270/Q2MG7RN9
					More data for this Ligand-Target Pair