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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM354324'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM354324
PNG
(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Show SMILES COCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccc(CP(C)(C)=O)c4)C(C)C)c4ccccc34)n2)cc(OC)c1
Show InChI InChI=1S/C46H56N7O9P/c1-32(2)41-30-43(53(52-41)35-11-9-10-33(26-35)31-63(5,6)55)50-46(54)49-40-14-15-42(39-13-8-7-12-38(39)40)62-44-16-17-47-45(51-44)48-34-27-36(57-4)29-37(28-34)61-25-24-60-23-22-59-21-20-58-19-18-56-3/h7-17,26-30,32H,18-25,31H2,1-6H3,(H,47,48,51)(H2,49,50,54)
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US Patent
n/an/a 4n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9796742 (2017)


BindingDB Entry DOI: 10.7270/Q2KW5J5M
More data for this
Ligand-Target Pair