Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50007122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50007122 (CHEMBL3237576) Show SMILES COc1ccc(Nc2cc(N[C@@H]3CCOC[C@@H]3N)nnc2C(N)=O)nc1C(C)C |r| Show InChI InChI=1S/C19H27N7O3/c1-10(2)17-14(28-3)4-5-15(24-17)23-13-8-16(25-26-18(13)19(21)27)22-12-6-7-29-9-11(12)20/h4-5,8,10-12H,6-7,9,20H2,1-3H3,(H2,21,27)(H2,22,23,24,25)/t11-,12+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human SYK (360 to 635) using biotin-EPEGDYEEVLE as substrate preincubated for 10 mins followed by substrate/ATP/[33Pgamma]ATP addition ...				J Med Chem 57: 2683-91 (2014) Article DOI: 10.1021/jm401982j BindingDB Entry DOI: 10.7270/Q2HT2QTR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50007122 (CHEMBL3237576) Show SMILES COc1ccc(Nc2cc(N[C@@H]3CCOC[C@@H]3N)nnc2C(N)=O)nc1C(C)C |r| Show InChI InChI=1S/C19H27N7O3/c1-10(2)17-14(28-3)4-5-15(24-17)23-13-8-16(25-26-18(13)19(21)27)22-12-6-7-29-9-11(12)20/h4-5,8,10-12H,6-7,9,20H2,1-3H3,(H2,21,27)(H2,22,23,24,25)/t11-,12+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of SYK in human whole blood assessed as anti-human IgM-induced CD69 protein expression preincubated for 30 mins followed by anti-human IgM...				J Med Chem 57: 2683-91 (2014) Article DOI: 10.1021/jm401982j BindingDB Entry DOI: 10.7270/Q2HT2QTR
					More data for this Ligand-Target Pair