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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK [2-635]' and Ligand = 'BDBM211951'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK [2-635]


(Homo sapiens (Human))
BDBM211951
PNG
(US9290481, 1.2)
Show SMILES Cc1c[nH]c2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)cc(F)cc12 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.800n/an/an/an/a7.530



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...


US Patent US9290481 (2016)


BindingDB Entry DOI: 10.7270/Q2G15ZPR
More data for this
Ligand-Target Pair