Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM26424'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM26424 (7-[(3,5-dimethoxyphenyl)amino]-5-({[4-(hydroxymeth...) Show SMILES COc1cc(Nc2nc(NCc3ccc(CO)cc3)n3ccnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C23H24N6O4/c1-32-17-9-16(10-18(11-17)33-2)27-21-19(20(24)31)22-25-7-8-29(22)23(28-21)26-12-14-3-5-15(13-30)6-4-14/h3-11,27,30H,12-13H2,1-2H3,(H2,24,31)(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	7.6	30
Kissei Pharmaceutical Company					Assay Description A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...				Bioorg Med Chem 17: 284-94 (2009) Article DOI: 10.1016/j.bmc.2008.10.070 BindingDB Entry DOI: 10.7270/Q2FQ9TXB
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