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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM50083645'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM50083645
PNG
(CHEMBL324576 | [4-(6-Morpholin-4-yl-pyridin-3-yl)-...)
Show SMILES COc1cc(Nc2nccc(n2)-c2ccc(nc2)N2CCOCC2)cc(OC)c1OC
Show InChI InChI=1S/C22H25N5O4/c1-28-18-12-16(13-19(29-2)21(18)30-3)25-22-23-7-6-17(26-22)15-4-5-20(24-14-15)27-8-10-31-11-9-27/h4-7,12-14H,8-11H2,1-3H3,(H,23,25,26)
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Celltech Therapeutics Limited

Curated by ChEMBL


Assay Description
Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.

Bioorg Med Chem Lett 9: 3351-6 (2000)


BindingDB Entry DOI: 10.7270/Q29Z943G
More data for this
Ligand-Target Pair