Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM5088'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM5088 (1,2,4-Oxadiazole Analogue 14c | 4-[(2S)-2-[1-(3,4-...) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccc(F)c(F)c1)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 |r| Show InChI InChI=1S/C29H26F5N4O7P/c1-16(28-37-25(38-44-28)14-18-2-7-20(8-3-18)29(32,33)34)35-27(40)24(13-17-4-9-21(10-5-17)45-46(41,42)43)36-26(39)15-19-6-11-22(30)23(31)12-19/h2-12,16,24H,13-15H2,1H3,(H,35,40)(H,36,39)(H2,41,42,43)/t16-,24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc.					Assay Description Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...				J Med Chem 42: 4088-98 (1999) Article DOI: 10.1021/jm990229t BindingDB Entry DOI: 10.7270/Q27D2SBP
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