Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM5090'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM5090 (1,2,4-Oxadiazole Analogue 14e | 4-[(2S)-2-[1-(naph...) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccc2ccccc2c1)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 |r| Show InChI InChI=1S/C33H30F3N4O7P/c1-20(32-39-29(40-46-32)18-22-7-12-26(13-8-22)33(34,35)36)37-31(42)28(17-21-9-14-27(15-10-21)47-48(43,44)45)38-30(41)19-23-6-11-24-4-2-3-5-25(24)16-23/h2-16,20,28H,17-19H2,1H3,(H,37,42)(H,38,41)(H2,43,44,45)/t20-,28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc.					Assay Description Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...				J Med Chem 42: 4088-98 (1999) Article DOI: 10.1021/jm990229t BindingDB Entry DOI: 10.7270/Q27D2SBP
					More data for this Ligand-Target Pair