Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor TYRO3' and Ligand = 'BDBM397046'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397046 (US10442810, Example 110 | US10844069, Example 110 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(N4CCOCC4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H42N8O4/c1-24(2)37(48)44-15-13-27(14-16-44)33-21-30(34-35(39)40-23-41-46(33)34)26-9-11-28(12-10-26)42-36(47)31-22-32(43-17-19-50-20-18-43)25(3)45(38(31)49)29-7-5-4-6-8-29/h4-12,21-24,27H,13-20H2,1-3H3,(H,42,47)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397046 (US10442810, Example 110 | US10844069, Example 110 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(N4CCOCC4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H42N8O4/c1-24(2)37(48)44-15-13-27(14-16-44)33-21-30(34-35(39)40-23-41-46(33)34)26-9-11-28(12-10-26)42-36(47)31-22-32(43-17-19-50-20-18-43)25(3)45(38(31)49)29-7-5-4-6-8-29/h4-12,21-24,27H,13-20H2,1-3H3,(H,42,47)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				US Patent US10844069 (2020) BindingDB Entry DOI: 10.7270/Q2CZ3B73
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397046 (US10442810, Example 110 | US10844069, Example 110 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(N4CCOCC4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H42N8O4/c1-24(2)37(48)44-15-13-27(14-16-44)33-21-30(34-35(39)40-23-41-46(33)34)26-9-11-28(12-10-26)42-36(47)31-22-32(43-17-19-50-20-18-43)25(3)45(38(31)49)29-7-5-4-6-8-29/h4-12,21-24,27H,13-20H2,1-3H3,(H,42,47)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Tyro3, and Mer:The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolve...				J Med Chem 52: 3576-85 (2009) BindingDB Entry DOI: 10.7270/Q2FB5593
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397046 (US10442810, Example 110 | US10844069, Example 110 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(N4CCOCC4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H42N8O4/c1-24(2)37(48)44-15-13-27(14-16-44)33-21-30(34-35(39)40-23-41-46(33)34)26-9-11-28(12-10-26)42-36(47)31-22-32(43-17-19-50-20-18-43)25(3)45(38(31)49)29-7-5-4-6-8-29/h4-12,21-24,27H,13-20H2,1-3H3,(H,42,47)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				US Patent US10442810 (2019) BindingDB Entry DOI: 10.7270/Q2NG4T17
					More data for this Ligand-Target Pair