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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor TYRO3' and Ligand = 'BDBM50466394'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))		BDBM50466394
PNG
(CHEMBL4285809)
Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3c(Br)cnc4[nH]cnc34)c(F)c2)c1=O
Show InChI InChI=1S/C24H14BrF2N5O3/c25-17-11-28-22-20(29-12-30-22)21(17)35-19-8-5-14(10-18(19)27)31-23(33)16-2-1-9-32(24(16)34)15-6-3-13(26)4-7-15/h1-12H,(H,31,33)(H,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



PSL Research University

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...

Bioorg Med Chem 26: 5510-5530 (2018)


Article DOI: 10.1016/j.bmc.2018.09.031
BindingDB Entry DOI: 10.7270/Q27S7RGR
More data for this
Ligand-Target Pair