Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50259862![]() (13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Catholic University of Daegu Curated by ChEMBL | Assay Description Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft... | Bioorg Med Chem 23: 3730-7 (2015) Article DOI: 10.1016/j.bmc.2015.04.007 BindingDB Entry DOI: 10.7270/Q25T3N81 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50259862![]() (13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Catholic University of Daegu Curated by ChEMBL | Assay Description Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft... | Bioorg Med Chem 23: 3730-7 (2015) Article DOI: 10.1016/j.bmc.2015.04.007 BindingDB Entry DOI: 10.7270/Q25T3N81 | |||||||||||
More data for this Ligand-Target Pair |