Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50320880'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50320880 (7,7-Dimethyl-2-phenyl-4-p-tolyl-4,6,7,8-tetrahydro...) Show SMILES Cc1ccc(cc1)C1=CC(C2C(=O)CC(C)(C)CC2=N1)c1ccccc1 |c:20,t:8| Show InChI InChI=1S/C24H25NO/c1-16-9-11-18(12-10-16)20-13-19(17-7-5-4-6-8-17)23-21(25-20)14-24(2,3)15-22(23)26/h4-13,19,23H,14-15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B assessed as p-nitrophenolate ion production pretreated for 10 mins measured after 30 mins				Bioorg Med Chem 18: 4138-48 (2010) Article DOI: 10.1016/j.bmc.2009.11.061 BindingDB Entry DOI: 10.7270/Q2DJ5FSF
					More data for this Ligand-Target Pair