Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM446453'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM446453 ((R)-1-((7-cyano-2-(3′-(7-(((R)-3-hydroxypyrr...) Show SMILES Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@H](O)C3)cc2n1 |r| Show InChI InChI=1S/C41H40N8O4/c1-23-31(6-4-8-33(23)40-47-36-15-26(14-29(17-42)38(36)53-40)19-48-12-10-28(21-48)41(51)52)32-7-5-9-34(24(32)2)46-39-37-35(44-25(3)45-39)16-27(18-43-37)20-49-13-11-30(50)22-49/h4-9,14-16,18,28,30,50H,10-13,19-22H2,1-3H3,(H,51,52)(H,44,45,46)/t28-,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description U2OS/PD-L1 cells (DiscoveRx Corporation) were maintained in McCoy's 5A medium with addition of 10% FBS, 0.25 μg/ml Puromycin. After removing...				US Patent US10669271 (2020) BindingDB Entry DOI: 10.7270/Q2MG7SJC
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM446453 ((R)-1-((7-cyano-2-(3′-(7-(((R)-3-hydroxypyrr...) Show SMILES Cc1nc(Nc2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@H](C5)C(O)=O)cc(C#N)c4o3)c2C)c2ncc(CN3CC[C@@H](O)C3)cc2n1 |r| Show InChI InChI=1S/C41H40N8O4/c1-23-31(6-4-8-33(23)40-47-36-15-26(14-29(17-42)38(36)53-40)19-48-12-10-28(21-48)41(51)52)32-7-5-9-34(24(32)2)46-39-37-35(44-25(3)45-39)16-27(18-43-37)20-49-13-11-30(50)22-49/h4-9,14-16,18,28,30,50H,10-13,19-22H2,1-3H3,(H,51,52)(H,44,45,46)/t28-,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description U2OS/PD-L1 cells (DiscoveRx Corporation) were maintained in McCoy's 5A medium with addition of 10% FBS, 0.25 μg/ml Puromycin. After removing...				US Patent US10669271 (2020) BindingDB Entry DOI: 10.7270/Q2MG7SJC
					More data for this Ligand-Target Pair