Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM479344'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM479344 ((3-((3S,4)S-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@@H](COCC6CC6)C[C@H]5COc34)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C29H40N6O4S/c1-18-26(30)29(17-39-18)5-8-34(9-6-29)27-22(13-36)33-24(11-32-27)40-23-4-7-31-28-25(23)38-16-21-10-20(12-35(21)28)15-37-14-19-2-3-19/h4,7,11,18-21,26,36H,2-3,5-6,8-10,12-17,30H2,1H3/t18-,20-,21-,26+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6J2V
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM479344 ((3-((3S,4)S-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@@H](COCC6CC6)C[C@H]5COc34)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C29H40N6O4S/c1-18-26(30)29(17-39-18)5-8-34(9-6-29)27-22(13-36)33-24(11-32-27)40-23-4-7-31-28-25(23)38-16-21-10-20(12-35(21)28)15-37-14-19-2-3-19/h4,7,11,18-21,26,36H,2-3,5-6,8-10,12-17,30H2,1H3/t18-,20-,21-,26+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Nikang Therapeutics, Inc. US Patent					Assay Description SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...				US Patent US10894797 (2021) BindingDB Entry DOI: 10.7270/Q2222XV2
					More data for this Ligand-Target Pair