Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human)) | BDBM492366![]() (US10975080, Example 64) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS AG US Patent | Assay Description SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st... | US Patent US10975080 (2021) BindingDB Entry DOI: 10.7270/Q2TM7F60 | |||||||||||
More data for this Ligand-Target Pair |