Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM503309'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM503309 (6-amino-2-[(1R)-1-amino-3,3- difluoro-8-azaspiro[4...) Show SMILES N[C@@H]1CC(F)(F)CC11CCN(CC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O |r,wD:1.0,(6.15,.34,;5.83,-1.16,;6.86,-2.31,;6.09,-3.64,;7.58,-4.04,;5.73,-5.14,;4.59,-3.32,;4.42,-1.79,;3.09,-2.56,;1.76,-1.79,;1.76,-.25,;3.09,.52,;4.42,-.25,;.42,.52,;.42,2.06,;-.91,2.83,;-.91,4.37,;-2.24,2.06,;-3.58,2.83,;-3.58,4.37,;-4.91,5.14,;-6.25,4.37,;-6.25,2.83,;-7.58,2.06,;-4.91,2.06,;-4.91,.52,;-2.24,.52,;-.91,-.25,;-3.33,-.57,;-2.74,-1.99,;-4.87,-.57,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JS9VKW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM503309 (6-amino-2-[(1R)-1-amino-3,3- difluoro-8-azaspiro[4...) Show SMILES N[C@@H]1CC(F)(F)CC11CCN(CC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O |r,wD:1.0,(6.15,.34,;5.83,-1.16,;6.86,-2.31,;6.09,-3.64,;7.58,-4.04,;5.73,-5.14,;4.59,-3.32,;4.42,-1.79,;3.09,-2.56,;1.76,-1.79,;1.76,-.25,;3.09,.52,;4.42,-.25,;.42,.52,;.42,2.06,;-.91,2.83,;-.91,4.37,;-2.24,2.06,;-3.58,2.83,;-3.58,4.37,;-4.91,5.14,;-6.25,4.37,;-6.25,2.83,;-7.58,2.06,;-4.91,2.06,;-4.91,.52,;-2.24,.52,;-.91,-.25,;-3.33,-.57,;-2.74,-1.99,;-4.87,-.57,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930X9N
					More data for this Ligand-Target Pair