Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM503312'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM503312 (6-amino-2-[8-(aminomethyl)-6- azaspiro[3.4]octan-6...) Show SMILES NCC1CN(CC11CCC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O |(6.3,-.49,;5.67,-1.9,;4.14,-2.06,;3.11,-.92,;1.7,-1.54,;1.86,-3.08,;3.37,-3.4,;2.82,-4.83,;4.26,-5.39,;4.81,-3.95,;.37,-.77,;.37,.77,;-.96,1.54,;-.96,3.08,;-2.3,.77,;-3.63,1.54,;-4.96,.77,;-6.3,1.54,;-6.3,3.08,;-4.96,3.85,;-4.96,5.39,;-3.63,3.08,;-2.3,3.85,;-2.3,-.77,;-.96,-1.54,;-3.63,-1.54,;-3.63,-3.08,;-4.96,-.77,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JS9VKW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM503312 (6-amino-2-[8-(aminomethyl)-6- azaspiro[3.4]octan-6...) Show SMILES NCC1CN(CC11CCC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O |(6.3,-.49,;5.67,-1.9,;4.14,-2.06,;3.11,-.92,;1.7,-1.54,;1.86,-3.08,;3.37,-3.4,;2.82,-4.83,;4.26,-5.39,;4.81,-3.95,;.37,-.77,;.37,.77,;-.96,1.54,;-.96,3.08,;-2.3,.77,;-3.63,1.54,;-4.96,.77,;-6.3,1.54,;-6.3,3.08,;-4.96,3.85,;-4.96,5.39,;-3.63,3.08,;-2.3,3.85,;-2.3,-.77,;-.96,-1.54,;-3.63,-1.54,;-3.63,-3.08,;-4.96,-.77,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930X9N
					More data for this Ligand-Target Pair