Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM50463369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50463369 (CHEMBL4240521) Show SMILES CC(=O)C1=C(O)C=C2Oc3c4C(=O)\C(Oc4c(C)c(O)c3[C@@]2(C)C1=O)=C\c1cc(Br)cc(Br)c1 |r,c:3,t:6| Show InChI InChI=1S/C25H16Br2O7/c1-9-20(30)19-23(34-16-8-14(29)17(10(2)28)24(32)25(16,19)3)18-21(31)15(33-22(9)18)6-11-4-12(26)7-13(27)5-11/h4-8,29-30H,1-3H3/b15-6-/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...				Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50463369 (CHEMBL4240521) Show SMILES CC(=O)C1=C(O)C=C2Oc3c4C(=O)\C(Oc4c(C)c(O)c3[C@@]2(C)C1=O)=C\c1cc(Br)cc(Br)c1 |r,c:3,t:6| Show InChI InChI=1S/C25H16Br2O7/c1-9-20(30)19-23(34-16-8-14(29)17(10(2)28)24(32)25(16,19)3)18-21(31)15(33-22(9)18)6-11-4-12(26)7-13(27)5-11/h4-8,29-30H,1-3H3/b15-6-/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured after 20 mins by electrophoresis...				Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50463369 (CHEMBL4240521) Show SMILES CC(=O)C1=C(O)C=C2Oc3c4C(=O)\C(Oc4c(C)c(O)c3[C@@]2(C)C1=O)=C\c1cc(Br)cc(Br)c1 |r,c:3,t:6| Show InChI InChI=1S/C25H16Br2O7/c1-9-20(30)19-23(34-16-8-14(29)17(10(2)28)24(32)25(16,19)3)18-21(31)15(33-22(9)18)6-11-4-12(26)7-13(27)5-11/h4-8,29-30H,1-3H3/b15-6-/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-tyrosine)-3' as substrate measured after 5 mins by electrophore...				Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM
					More data for this Ligand-Target Pair