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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM50507147'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosyl-DNA phosphodiesterase 1


(Homo sapiens (Human))		BDBM50507147
PNG
(CHEMBL4464001)
Show SMILES CNc1nc(cs1)-c1c2OC3=CC(O)=C(C(C)=O)C(=O)[C@]3(C)c2c(O)c(C)c1O |r,t:11,14|
Show InChI InChI=1S/C20H18N2O6S/c1-7-15(25)13(9-6-29-19(21-4)22-9)17-14(16(7)26)20(3)11(28-17)5-10(24)12(8(2)23)18(20)27/h5-6,24-26H,1-4H3,(H,21,22)/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



Siberian Branch of the Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...

Eur J Med Chem 161: 581-593 (2019)


Article DOI: 10.1016/j.ejmech.2018.10.055
BindingDB Entry DOI: 10.7270/Q2B56P1F
More data for this
Ligand-Target Pair