Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 2' and Ligand = 'BDBM50438850'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50438850 (CHEMBL2420478) Show SMILES O=c1nc2n(-c3ccc4cn[nH]c4c3)c3cc(ccc3cc2c(=O)[nH]1)C#N Show InChI InChI=1S/C19H10N6O2/c20-8-10-1-2-11-6-14-17(22-19(27)23-18(14)26)25(16(11)5-10)13-4-3-12-9-21-24-15(12)7-13/h1-7,9H,(H,21,24)(H,23,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of TDP2 (unknown origin) using 5'-Y-TCCGTTGAAGCCTGCTTT-3' as substrate after 60 mins				J Med Chem 56: 6352-70 (2013) Article DOI: 10.1021/jm400568p BindingDB Entry DOI: 10.7270/Q2N017ZB
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50438850 (CHEMBL2420478) Show SMILES O=c1nc2n(-c3ccc4cn[nH]c4c3)c3cc(ccc3cc2c(=O)[nH]1)C#N Show InChI InChI=1S/C19H10N6O2/c20-8-10-1-2-11-6-14-17(22-19(27)23-18(14)26)25(16(11)5-10)13-4-3-12-9-21-24-15(12)7-13/h1-7,9H,(H,21,24)(H,23,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 mins				J Med Chem 56: 6352-70 (2013) Article DOI: 10.1021/jm400568p BindingDB Entry DOI: 10.7270/Q2N017ZB
					More data for this Ligand-Target Pair