BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'U5 small nuclear ribonucleoprotein 200 kDa helicase' and Ligand = 'BDBM50239864'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
U5 small nuclear ribonucleoprotein 200 kDa helicase


(Homo sapiens (Human))		BDBM50239864
PNG
(CHEMBL4074763)
Show SMILES CN1C(=O)N(Cc2cn(Cc3ccccc3)c(=O)cc12)c1cc2OC(CCc2cc1C)c1ncccc1F
Show InChI InChI=1S/C30H27FN4O3/c1-19-13-21-10-11-26(29-23(31)9-6-12-32-29)38-27(21)14-24(19)35-18-22-17-34(16-20-7-4-3-5-8-20)28(36)15-25(22)33(2)30(35)37/h3-9,12-15,17,26H,10-11,16,18H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Takeda California Inc.

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...

J Med Chem 60: 5759-5771 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00461
BindingDB Entry DOI: 10.7270/Q2MC925G
More data for this
Ligand-Target Pair