Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'U5 small nuclear ribonucleoprotein 200 kDa helicase' and Ligand = 'BDBM50239870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human))	BDBM50239870 (CHEMBL4061514) Show SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C27H23N3O3/c31-26-15-23-22(17-29(26)16-20-9-3-1-4-10-20)18-30(27(32)28-23)24-13-7-8-14-25(24)33-19-21-11-5-2-6-12-21/h1-15,17H,16,18-19H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...				J Med Chem 60: 5759-5771 (2017) Article DOI: 10.1021/acs.jmedchem.7b00461 BindingDB Entry DOI: 10.7270/Q2MC925G
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