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Found 1 hit Enz. Inhib. hit(s) with Target = 'U5 small nuclear ribonucleoprotein 200 kDa helicase' and Ligand = 'BDBM50260438'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
U5 small nuclear ribonucleoprotein 200 kDa helicase


(Homo sapiens (Human))		BDBM50260438
PNG
(CHEMBL4088975)
Show SMILES CC(C)C[C@H]1C[C@@H](C)[C@@]2(N1C(=O)c1ccccn1)C(=O)Nc1ccccc21 |r|
Show InChI InChI=1S/C22H25N3O2/c1-14(2)12-16-13-15(3)22(17-8-4-5-9-18(17)24-21(22)27)25(16)20(26)19-10-6-7-11-23-19/h4-11,14-16H,12-13H2,1-3H3,(H,24,27)/t15-,16+,22+/m1/s1
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PubMed
n/an/a 360n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...

Bioorg Med Chem 25: 4753-4767 (2017)


Article DOI: 10.1016/j.bmc.2017.07.017
BindingDB Entry DOI: 10.7270/Q27M0BDH
More data for this
Ligand-Target Pair