Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM324894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324894 (7-cyclopropyl-2-(2- | US10189841, Compound I-100 |...) Show SMILES Cn1cc(nc1-c1ccc(Cn2c3nc(ncc3n(C3CC3)c2=O)-c2ccccc2C2CC2)cc1)C(F)(F)F Show InChI InChI=1S/C29H25F3N6O/c1-36-16-24(29(30,31)32)34-26(36)19-8-6-17(7-9-19)15-37-27-23(38(28(37)39)20-12-13-20)14-33-25(35-27)22-5-3-2-4-21(22)18-10-11-18/h2-9,14,16,18,20H,10-13,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324894 (7-cyclopropyl-2-(2- | US10189841, Compound I-100 |...) Show SMILES Cn1cc(nc1-c1ccc(Cn2c3nc(ncc3n(C3CC3)c2=O)-c2ccccc2C2CC2)cc1)C(F)(F)F Show InChI InChI=1S/C29H25F3N6O/c1-36-16-24(29(30,31)32)34-26(36)19-8-6-17(7-9-19)15-37-27-23(38(28(37)39)20-12-13-20)14-33-25(35-27)22-5-3-2-4-21(22)18-10-11-18/h2-9,14,16,18,20H,10-13,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324894 (7-cyclopropyl-2-(2- | US10189841, Compound I-100 |...) Show SMILES Cn1cc(nc1-c1ccc(Cn2c3nc(ncc3n(C3CC3)c2=O)-c2ccccc2C2CC2)cc1)C(F)(F)F Show InChI InChI=1S/C29H25F3N6O/c1-36-16-24(29(30,31)32)34-26(36)19-8-6-17(7-9-19)15-37-27-23(38(28(37)39)20-12-13-20)14-33-25(35-27)22-5-3-2-4-21(22)18-10-11-18/h2-9,14,16,18,20H,10-13,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair