Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM324902'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324902 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2n(C)c(=O)n(c2n1)C1(CC1)c1ccc(cc1)-c1nc(cn1C)C(F)(F)F Show InChI InChI=1S/C28H26F3N7O/c1-16(2)22-19(6-5-13-32-22)23-33-14-20-25(35-23)38(26(39)37(20)4)27(11-12-27)18-9-7-17(8-10-18)24-34-21(15-36(24)3)28(29,30)31/h5-10,13-16H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324902 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2n(C)c(=O)n(c2n1)C1(CC1)c1ccc(cc1)-c1nc(cn1C)C(F)(F)F Show InChI InChI=1S/C28H26F3N7O/c1-16(2)22-19(6-5-13-32-22)23-33-14-20-25(35-23)38(26(39)37(20)4)27(11-12-27)18-9-7-17(8-10-18)24-34-21(15-36(24)3)28(29,30)31/h5-10,13-16H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324902 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2n(C)c(=O)n(c2n1)C1(CC1)c1ccc(cc1)-c1nc(cn1C)C(F)(F)F Show InChI InChI=1S/C28H26F3N7O/c1-16(2)22-19(6-5-13-32-22)23-33-14-20-25(35-23)38(26(39)37(20)4)27(11-12-27)18-9-7-17(8-10-18)24-34-21(15-36(24)3)28(29,30)31/h5-10,13-16H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair