Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM324914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324914 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES COCCn1c2cnc(nc2n(Cc2ccc(cc2)-c2nc(cn2C)C(F)(F)F)c1=O)-c1cccnc1C(C)C Show InChI InChI=1S/C28H28F3N7O2/c1-17(2)23-20(6-5-11-32-23)24-33-14-21-26(35-24)38(27(39)37(21)12-13-40-4)15-18-7-9-19(10-8-18)25-34-22(16-36(25)3)28(29,30)31/h5-11,14,16-17H,12-13,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324914 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES COCCn1c2cnc(nc2n(Cc2ccc(cc2)-c2nc(cn2C)C(F)(F)F)c1=O)-c1cccnc1C(C)C Show InChI InChI=1S/C28H28F3N7O2/c1-17(2)23-20(6-5-11-32-23)24-33-14-21-26(35-24)38(27(39)37(21)12-13-40-4)15-18-7-9-19(10-8-18)25-34-22(16-36(25)3)28(29,30)31/h5-11,14,16-17H,12-13,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324914 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES COCCn1c2cnc(nc2n(Cc2ccc(cc2)-c2nc(cn2C)C(F)(F)F)c1=O)-c1cccnc1C(C)C Show InChI InChI=1S/C28H28F3N7O2/c1-17(2)23-20(6-5-11-32-23)24-33-14-21-26(35-24)38(27(39)37(21)12-13-40-4)15-18-7-9-19(10-8-18)25-34-22(16-36(25)3)28(29,30)31/h5-11,14,16-17H,12-13,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair