Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 30' and Ligand = 'BDBM489730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489730 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCCCC3)cccc12 |r| Show InChI InChI=1S/C31H39N3O4S/c1-31(2,3)34-39(37,38)28-20-12-17-24-25(28)18-11-19-26(24)32-30(36)27(21-22-13-7-6-8-14-22)33-29(35)23-15-9-4-5-10-16-23/h6-8,11-14,17-20,23,27,34H,4-5,9-10,15-16,21H2,1-3H3,(H,32,36)(H,33,35)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM489730 ((S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-...) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCCCC3)cccc12 |r| Show InChI InChI=1S/C31H39N3O4S/c1-31(2,3)34-39(37,38)28-20-12-17-24-25(28)18-11-19-26(24)32-30(36)27(21-22-13-7-6-8-14-22)33-29(35)23-15-9-4-5-10-16-23/h6-8,11-14,17-20,23,27,34H,4-5,9-10,15-16,21H2,1-3H3,(H,32,36)(H,33,35)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mitobridge, Inc. US Patent					Assay Description The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...				US Patent US10968172 (2021) BindingDB Entry DOI: 10.7270/Q2P27274
					More data for this Ligand-Target Pair