Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1' and Ligand = 'BDBM445137'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445137 ((S)-2-(4-(2-Aminopyridin-4-yl)indoline-1-carbonyl)...) Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCc2c1cccc2-c1ccnc(N)c1 |r| Show InChI InChI=1S/C23H28N4O3/c1-23(2,3)30-22(29)27-12-5-8-19(27)21(28)26-13-10-17-16(6-4-7-18(17)26)15-9-11-25-20(24)14-15/h4,6-7,9,11,14,19H,5,8,10,12-13H2,1-3H3,(H2,24,25)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445137 ((S)-2-(4-(2-Aminopyridin-4-yl)indoline-1-carbonyl)...) Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCc2c1cccc2-c1ccnc(N)c1 |r| Show InChI InChI=1S/C23H28N4O3/c1-23(2,3)30-22(29)27-12-5-8-19(27)21(28)26-13-10-17-16(6-4-7-18(17)26)15-9-11-25-20(24)14-15/h4,6-7,9,11,14,19H,5,8,10,12-13H2,1-3H3,(H2,24,25)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair