Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1' and Ligand = 'BDBM445159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445159 (4-(1-(cyano-L-prolyl)indolin- 4-yl)nicotinonitrile...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1ccncc1C#N Show InChI InChI=1S/C20H17N5O/c21-11-14-12-23-8-6-15(14)16-3-1-4-18-17(16)7-10-25(18)20(26)19-5-2-9-24(19)13-22/h1,3-4,6,8,12,19H,2,5,7,9-10H2/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445159 (4-(1-(cyano-L-prolyl)indolin- 4-yl)nicotinonitrile...) Show SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1ccncc1C#N Show InChI InChI=1S/C20H17N5O/c21-11-14-12-23-8-6-15(14)16-3-1-4-18-17(16)7-10-25(18)20(26)19-5-2-9-24(19)13-22/h1,3-4,6,8,12,19H,2,5,7,9-10H2/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair