Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1' and Ligand = 'BDBM445169'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445169 ((S)-1-cyano-N-(4-(3- cyanophenyl)thiazol-2-yl)- N-...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H15N5OS/c1-21(16(23)15-6-3-7-22(15)11-19)17-20-14(10-24-17)13-5-2-4-12(8-13)9-18/h2,4-5,8,10,15H,3,6-7H2,1H3/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445169 ((S)-1-cyano-N-(4-(3- cyanophenyl)thiazol-2-yl)- N-...) Show SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1cccc(c1)C#N Show InChI InChI=1S/C17H15N5OS/c1-21(16(23)15-6-3-7-22(15)11-19)17-20-14(10-24-17)13-5-2-4-12(8-13)9-18/h2,4-5,8,10,15H,3,6-7H2,1H3/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair