Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme ATG7' and Ligand = 'BDBM476069'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin-like modifier-activating enzyme ATG7 (Homo sapiens (Human))	BDBM476069 (US10865208, Compound I-126 | [(2R,3R,4S,5R)-5-{4-a...) Show SMILES Nc1ncnc2n(nc(Sc3ccc(F)cc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@@H]1F |r| Show InChI InChI=1S/C16H16F2N6O5S2/c17-7-1-3-8(4-2-7)30-15-10-13(19)21-6-22-14(10)24(23-15)16-11(18)12(25)9(29-16)5-28-31(20,26)27/h1-4,6,9,11-12,16,25H,5H2,(H2,19,21,22)(H2,20,26,27)/t9-,11+,12-,16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...				US Patent US10865208 (2020) BindingDB Entry DOI: 10.7270/Q23B6366
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