BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM50072855'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))		BDBM50072855
PNG
(1-[3-(3-Diaminomethyl-phenyl)-2-(2,4,6-triisopropy...)
Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NC(Cc1cccc(c1)C(N)N)C(=O)N1CCCC(C1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C38H53N5O4S/c1-24(2)31-20-32(25(3)4)35(33(21-31)26(5)6)48(46,47)42-34(19-28-14-10-15-29(18-28)36(39)40)38(45)43-17-11-16-30(23-43)37(44)41-22-27-12-8-7-9-13-27/h7-10,12-15,18,20-21,24-26,30,34,36,42H,11,16-17,19,22-23,39-40H2,1-6H3,(H,41,44)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.60E+3n/an/an/an/an/an/an/an/a



Institut für Biochemie

Curated by ChEMBL


Assay Description
Inhibitory activity against human urokinase plasminogen activator expressed as dissociation constant

J Med Chem 41: 5445-56 (1999)


Article DOI: 10.1021/jm981068g
BindingDB Entry DOI: 10.7270/Q2KK99ZF
More data for this
Ligand-Target Pair