Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' and Ligand = 'BDBM102341'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM102341 (US10562854, No. B14 | US8536181, B14 | US9278930, ...) Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aerpio Therapeutics Inc. US Patent					Assay Description ELISA assay using VEGF.				US Patent US8536181 (2013) BindingDB Entry DOI: 10.7270/Q2D21W79
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM102341 (US10562854, No. B14 | US8536181, B14 | US9278930, ...) Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description VEGF: HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following ove...				US Patent US10562854 (2020) BindingDB Entry DOI: 10.7270/Q2668GK0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM102341 (US10562854, No. B14 | US8536181, B14 | US9278930, ...) Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US9278930 (2016) BindingDB Entry DOI: 10.7270/Q24J0CZG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM102341 (US10562854, No. B14 | US8536181, B14 | US9278930, ...) Show SMILES Oc1c(CN2CCN(CC2)c2ccc(Cl)nn2)ccn(Cc2ccccc2)c1=O Show InChI InChI=1S/C21H22ClN5O2/c22-18-6-7-19(24-23-18)26-12-10-25(11-13-26)15-17-8-9-27(21(29)20(17)28)14-16-4-2-1-3-5-16/h1-9,28H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aerpio Therapeutics Inc. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US8778412 (2014) BindingDB Entry DOI: 10.7270/Q2WS8RZ9
					More data for this Ligand-Target Pair