Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' and Ligand = 'BDBM126621'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM126621 (US10562854, No. B5 | US8778412, B5 | US9278930, B5) Show SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O |r| Show InChI InChI=1S/C19H24N2O3/c22-12-9-17-7-4-10-20(17)14-16-8-11-21(19(24)18(16)23)13-15-5-2-1-3-6-15/h1-3,5-6,8,11,17,22-23H,4,7,9-10,12-14H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aerpio Therapeutics Inc. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US8778412 (2014) BindingDB Entry DOI: 10.7270/Q2WS8RZ9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM126621 (US10562854, No. B5 | US8778412, B5 | US9278930, B5) Show SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O |r| Show InChI InChI=1S/C19H24N2O3/c22-12-9-17-7-4-10-20(17)14-16-8-11-21(19(24)18(16)23)13-15-5-2-1-3-6-15/h1-3,5-6,8,11,17,22-23H,4,7,9-10,12-14H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description VEGF: HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following ove...				US Patent US10562854 (2020) BindingDB Entry DOI: 10.7270/Q2668GK0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM126621 (US10562854, No. B5 | US8778412, B5 | US9278930, B5) Show SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O |r| Show InChI InChI=1S/C19H24N2O3/c22-12-9-17-7-4-10-20(17)14-16-8-11-21(19(24)18(16)23)13-15-5-2-1-3-6-15/h1-3,5-6,8,11,17,22-23H,4,7,9-10,12-14H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AERPIO THERAPEUTICS, INC. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US9278930 (2016) BindingDB Entry DOI: 10.7270/Q24J0CZG
					More data for this Ligand-Target Pair