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Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1/2/3' and Ligand = 'BDBM50475105'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475105
PNG
(CHEMBL189605)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Br)cc1Cl
Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-1-6-11(12(16)7-8)13(18)17-21(19,20)10-4-2-9(15)3-5-10/h1-7H,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair