BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1/2/3' and Ligand = 'BDBM50475127'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475127
PNG
(CHEMBL189826)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C13H9Cl2NO3S/c14-9-5-7-10(8-6-9)20(18,19)16-13(17)11-3-1-2-4-12(11)15/h1-8H,(H,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair