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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50209887'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50209887
PNG
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)
Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11|
Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 379n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2 in presence of 1 uM ATP


Bioorg Med Chem 15: 3635-48 (2007)


Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50209887
PNG
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)
Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11|
Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2 in presence of 1 mM ATP


Bioorg Med Chem 15: 3635-48 (2007)


Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8
More data for this
Ligand-Target Pair