Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50308188'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of recombinant VEGFR2 using poly(Glu,Tyr)4 as substrate assessed as inhibition of [33P]Phosphate incorporation into substrate after 80 min...				Eur J Med Chem 53: 254-63 (2012) Article DOI: 10.1016/j.ejmech.2012.04.007 BindingDB Entry DOI: 10.7270/Q2W66MT7
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair