Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50401289'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50401289 (CHEMBL2204529) Show SMILES CC(=O)Nc1nc2cnc(Nc3cc(NC(=O)c4cccc(c4Cl)C4(CC4)C#N)ccc3C)nc2s1 Show InChI InChI=1S/C25H20ClN7O2S/c1-13-6-7-15(30-21(35)16-4-3-5-17(20(16)26)25(12-27)8-9-25)10-18(13)31-23-28-11-19-22(33-23)36-24(32-19)29-14(2)34/h3-7,10-11H,8-9H2,1-2H3,(H,30,35)(H,28,31,33)(H,29,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUVEC assessed as reduction of VGF-stimulated cell proliferation after 5 days				Bioorg Med Chem 20: 5600-15 (2012) Article DOI: 10.1016/j.bmc.2012.07.032 BindingDB Entry DOI: 10.7270/Q2765GH8
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