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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50518789'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50518789
PNG
(CHEMBL4473548)
Show SMILES C[C@@H]1CN(C(=O)CCCC(=O)N2C[C@@H](C)c3c2cc(O)c2ccccc32)c2cc(O)c3ccccc3c12 |r|
Show InChI InChI=1S/C31H30N2O4/c1-18-16-32(24-14-26(34)20-8-3-5-10-22(20)30(18)24)28(36)12-7-13-29(37)33-17-19(2)31-23-11-6-4-9-21(23)27(35)15-25(31)33/h3-6,8-11,14-15,18-19,34-35H,7,12-13,16-17H2,1-2H3/t18-,19-/m1/s1
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PC cid
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Article
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n/an/a 330n/an/an/an/an/an/a



Albert Ludwigs University Freiburg

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...

J Nat Prod 82: 16-26 (2019)


Article DOI: 10.1021/acs.jnatprod.8b00233
BindingDB Entry DOI: 10.7270/Q2FX7DVS
More data for this
Ligand-Target Pair