Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50135415 (3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL | Assay Description Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptor | Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50135415 (3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL | Assay Description Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cells | Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3 | |||||||||||
More data for this Ligand-Target Pair |