Found 2 hits Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM50016316' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vasopressin V2 receptor
(BOVINE) | BDBM50016316
(CHEMBL413706 | [Phe2MeAla7]AVP (Arginine-vasopress...)Show SMILES C[C@@H](N(C)C(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O Show InChI InChI=1S/C45H65N15O11S2/c1-24(37(64)54-28(14-9-17-52-45(50)51)39(66)53-21-36(49)63)60(2)44(71)33-23-73-72-22-27(46)38(65)56-30(18-25-10-5-3-6-11-25)42(69)57-31(19-26-12-7-4-8-13-26)41(68)55-29(15-16-34(47)61)40(67)58-32(20-35(48)62)43(70)59-33/h3-8,10-13,24,27-33H,9,14-23,46H2,1-2H3,(H2,47,61)(H2,48,62)(H2,49,63)(H,53,66)(H,54,64)(H,55,68)(H,56,65)(H,57,69)(H,58,67)(H,59,70)(H4,50,51,52)/t24-,27-,28+,29-,30-,31+,32+,33+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against plasma membrane from bovine kidney inner medulla |
J Med Chem 29: 96-9 (1986)
BindingDB Entry DOI: 10.7270/Q2P849V1 |
More data for this
Ligand-Target Pair | |
Vasopressin V2 receptor
(BOVINE) | BDBM50016316
(CHEMBL413706 | [Phe2MeAla7]AVP (Arginine-vasopress...)Show SMILES C[C@@H](N(C)C(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O Show InChI InChI=1S/C45H65N15O11S2/c1-24(37(64)54-28(14-9-17-52-45(50)51)39(66)53-21-36(49)63)60(2)44(71)33-23-73-72-22-27(46)38(65)56-30(18-25-10-5-3-6-11-25)42(69)57-31(19-26-12-7-4-8-13-26)41(68)55-29(15-16-34(47)61)40(67)58-32(20-35(48)62)43(70)59-33/h3-8,10-13,24,27-33H,9,14-23,46H2,1-2H3,(H2,47,61)(H2,48,62)(H2,49,63)(H,53,66)(H,54,64)(H,55,68)(H,56,65)(H,57,69)(H,58,67)(H,59,70)(H4,50,51,52)/t24-,27-,28+,29-,30-,31+,32+,33+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity against plasma membrane from bovine kidney inner medulla using [3H]-AVP as a radioligand |
J Med Chem 29: 96-9 (1986)
BindingDB Entry DOI: 10.7270/Q2P849V1 |
More data for this
Ligand-Target Pair | |
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