Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1C' and Ligand = 'BDBM50534274'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50534274 (CHEMBL4457557) Show SMILES NC(=O)c1ccc(Cc2ccccc2)cc1-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C23H21NO3/c24-23(27)20-11-9-18(13-16-5-2-1-3-6-16)15-21(20)19-8-4-7-17(14-19)10-12-22(25)26/h1-9,11,14-15H,10,12-13H2,(H2,24,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca Curated by ChEMBL					Assay Description Inhibition of human Cav1.2 expressed in CHO cells by patch clamp assay				ACS Med Chem Lett 7: 884-889 (2016) Article DOI: 10.1021/acsmedchemlett.6b00188 BindingDB Entry DOI: 10.7270/Q23N26W0
					More data for this Ligand-Target Pair