Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50481872'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50481872 (CHEMBL1076546) Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CCCC1c1cccs1 Show InChI InChI=1S/C14H14ClNO2S2/c15-11-5-7-12(8-6-11)20(17,18)16-9-1-3-13(16)14-4-2-10-19-14/h2,4-8,10,13H,1,3,9H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Perugia Curated by ChEMBL					Assay Description Blockade of L-type calcium channel in Wistar rat cardiomyocytes assessed as inhibition of peak L-type barium current by whole cell patch clamp method				J Med Chem 52: 6637-48 (2009) Article DOI: 10.1021/jm9008696 BindingDB Entry DOI: 10.7270/Q2K35XG8
					More data for this Ligand-Target Pair