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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit beta-1' and Ligand = 'BDBM50481488'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-1


(Homo sapiens)		BDBM50481488
PNG
(CHEMBL597970)
Show SMILES Cc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H34N2O/c1-26-17-19-30(20-18-26)33(29-15-9-4-10-16-29)35-23-21-34(22-24-35)32(36)25-31(27-11-5-2-6-12-27)28-13-7-3-8-14-28/h2-20,31,33H,21-25H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Neuromed Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...

Bioorg Med Chem Lett 20: 1378-83 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR
More data for this
Ligand-Target Pair