Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50321403 (3-(4-(4-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay | Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW | |||||||||||
More data for this Ligand-Target Pair |