Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1G' and Ligand = 'BDBM50494712'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50494712 (CHEMBL3093774) Show SMILES COc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N(C)CCCCCN(C)C)c2ccc(cc2)-c2ccccc2)cc1 |c:13| Show InChI InChI=1S/C38H45N5O2/c1-41(2)25-11-6-12-26-42(3)38-40-35-16-10-9-15-34(35)36(27-37(44)39-28-29-17-23-33(45-4)24-18-29)43(38)32-21-19-31(20-22-32)30-13-7-5-8-14-30/h5,7-10,13-24,36H,6,11-12,25-28H2,1-4H3,(H,39,44)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of t-type Cav3.1 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of 50 ms depolarizing voltage step-induced curr...				Bioorg Med Chem Lett 23: 6656-62 (2013) Article DOI: 10.1016/j.bmcl.2013.10.049 BindingDB Entry DOI: 10.7270/Q28W3H80
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