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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50207234'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50207234
PNG
(CHEMBL3902262)
Show SMILES CC(C)Cc1cc(CNS(=O)(=O)c2ccccc2)nn1-c1ccccc1
Show InChI InChI=1S/C20H23N3O2S/c1-16(2)13-19-14-17(22-23(19)18-9-5-3-6-10-18)15-21-26(24,25)20-11-7-4-8-12-20/h3-12,14,16,21H,13,15H2,1-2H3
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Division of Bio-Medical Sciences& Technology, KIST School, Korea University of Science and Technology (UST), Gajungro 217, Youseong-gu, Daejeon 305-350, Republic of Korea.

Curated by ChEMBL


Assay Description
Inhibition of Cav3.2 alpha1H (unknown origin) expressed in HEK293 cells by whole-cell patch clamp assay

Bioorg Med Chem 25: 4677-4685 (2017)


Article DOI: 10.1016/j.bmc.2017.07.008
BindingDB Entry DOI: 10.7270/Q2JQ13H5
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50207234
PNG
(CHEMBL3902262)
Show SMILES CC(C)Cc1cc(CNS(=O)(=O)c2ccccc2)nn1-c1ccccc1
Show InChI InChI=1S/C20H23N3O2S/c1-16(2)13-19-14-17(22-23(19)18-9-5-3-6-10-18)15-21-26(24,25)20-11-7-4-8-12-20/h3-12,14,16,21H,13,15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Korea Institutes of Science and Technology (KIST)

Curated by ChEMBL


Assay Description
Inhibition of Cav3.2 alpha1H (unknown origin) expressed in HEK293 cells by whole-cell patch clamp method

Eur J Med Chem 123: 665-672 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.032
BindingDB Entry DOI: 10.7270/Q2ZK5JN6
More data for this
Ligand-Target Pair