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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50461278'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50461278
PNG
(CHEMBL4227740)
Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1
Show InChI InChI=1S/C24H22F3N3O2S/c25-24(26,27)17-4-8-19(9-5-17)32-20-10-11-21-22(14-20)33-23(30-21)29-15-16-2-6-18(7-3-16)31-13-1-12-28/h2-11,14H,1,12-13,15,28H2,(H,29,30)
PDB

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PC cid
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Article
PubMed
n/an/a 1.12E+5n/an/an/an/an/an/a



IITB-Monash Research Academy

Curated by ChEMBL


Assay Description
Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...

Bioorg Med Chem 26: 3046-3059 (2018)


Article DOI: 10.1016/j.bmc.2018.03.031
BindingDB Entry DOI: 10.7270/Q2BC4253
More data for this
Ligand-Target Pair